Tobannaan sano, PDRN waxay ku tiirsanayd soo saarista unugyada taranka ee salmon, iyadoo abuuraysa xaddidaadyo ku dhex jira xasilloonida sahayda, kala soocidda taxanaha DNA-da, iyo xakamaynta daahirnimada.
REC-gayaga RJMPDRN® (PDRN-ka Dib-u-habaynta Adduunka ee Koowaad)Waxay ka gudubtaa xaddidaadyadan iyada oo loo marayo injineerinka bayoolojiga ee horumarsan. Iyada oo aan laga helin ilo xayawaan oo lagu dhisay biosynthesis la xakameeyey, hal-abuurkani wuxuu adeegsadaa tignoolajiyada bayoolojiga. Taxanaha PDRN ee gaarka ah waxaa lagu soo bandhigaa iyada oo loo marayo vectors-ka dib-u-isku-dhafka ah waxaana lagu soo celiyaa halsano microbial ah. Tani waxay meesha ka saartaa ku tiirsanaanta walxaha laga helo kalluunka iyadoo la hubinayo in la waafajiyo heerarka sharciyeed ee EU, US, iyo kuwa caalamiga ah. Badeecadu waxay weli ku salaysan tahay DNA-da, bayoolaji ahaan sax ah, oo vegan ah.
Si ka duwan PDRN-ka caadiga ah (laga helo iyada oo loo marayo soo saarista aan la dooran), tiknoolajiyada dib-u-habaynta waxay awood u siinaysaa xakamaynta buuxda ee taxanaha DNA-da iyo dhererka jajabka. Taxanaha silsiladaha gaagaaban waxay bartilmaameedsadaan codsiyada ka hortagga bararka; taxanaha silsiladaha dhexe ilaa dheer waxay wanaajiyaan dib u soo noolaynta kolajka iyo hagaajinta maqaarka. Cabbiraadda baaxadda warshadaha waxaa lagu gaaraa iyada oo loo marayo isbeddelka kulaylka-shoogga ee la hagaajiyay, tignoolajiyada diyaarinta unugyada ee karti sare leh iyo nadiifinta tallaabooyin badan leh, si joogto ah u bixinta daahirnimo heer bayoolaji ah (≥99.5%).
Daraasad 28 maalmood ah oo ku saabsan waxtarka aadanaha ayaa lagu sameeyay 31 qof iyadoo la isticmaalayo xal biyood oo 0.1% RJMPDRN® REC ah.
Natiijooyinka Maalinta 14 (in vivo):
TEWL ↓9.58% (p<0.001)
Dabacsanaanta (R2) ↑19.33% (p<0.001)
Adkaanta (F4) ↓13.16% (p<0.001)
Tusmada Erythema ↓7.11% (p<0.001)
Tirada laalaabka ↓40.00% (p<0.001)
Meesha laalaabka ↓6.97% (p<0.001)
Dhererka laalaabku ↓8.14% (p=0.005)
Natiijooyinka Maalinta 28 (in vivo):
TEWL ↓17.37% (p<0.001)
Dabacsanaanta (R2) ↑30.11% (p<0.001)
Adkaanta (F4) ↓19.83% (p<0.001)
Tusmada Erythema ↓12.40% (p<0.001)
Tirada laalaabka ↓46.67% (p<0.001)
Meesha laalaabka ↓7.44% (p<0.001)
Dhererka laalaabku ↓11.44% (p=0.002)
RJMPDRN® REC (Dib-u-habaynta PDRN ee Adduunka ugu Horreysa)Waxay bixisaa isla hababka dayactirka maqaarka iyo dib-u-cusboonaysiinta sida PDRN-ka dhaqameed, laakiin leh isku-dheelitirnaan la hubo, soo-saarista khudradda, iyo badbaadada sharciyeed. Waa casriyeyn tignoolajiyadeed - ma aha oo kaliya beddel.
Waqtiga boostada: Maarso-20-2026