| Magaca astaanta | ActiTide™ AH3 (Liquefied 1000) |
| CAS Maya. | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Magaca INCI | Acetyl Hexapeptide-8; Glycerin; Butylene Glycol; Biyaha; Hydroxyacetophenone; 1,2-Hexanediol |
| Codsiga | Lotion, Serums, Maaskaro, Nadiifiyaha wejiga |
| Xidhmada | 1kg/dhalo |
| Muuqashada | Dareere cad oo hufan oo leh ur sifada |
| Solubility | Biyo milmaya |
| Shaqada | Taxanaha Peptide |
| Nolosha shelf | 2 sano |
| Kaydinta | Ku kaydi weelka si adag oo xiran meel qabow oo qallalan oo ah 2 - 8 ° C. |
| Qiyaasta | 3.0-10.0% |
Codsiga
Cilmi-baadhis lagu sameeyay hababka aasaasiga ah ee ka-hortagga laalaabku waxay horseedday helitaanka ActiTide ™ AH3, hexapeptide hal-abuur leh oo lagu sameeyay hab cilmiyeed laga soo bilaabo naqshad caqli-gal ah ilaa wax-soo-saarka GMP, oo leh natiijooyin wanaagsan.
ActiTide ™ AH3 waxay keentaa waxtarka yaraynta laalaabka oo la barbardhigi karo Botulinum Toxin Nooca A, iyadoo laga fogaanayo khataraha duritaanka iyo bixinta waxtarka-kharashka badan.
Faa'iidooyinka qurxinta:
ActiTide™ AH3 waxay yaraynaysaa laalaabkii qoto dheer ee ay sababto murqaha wejiga, oo leh saameyn la taaban karo oo ku saabsan wejiga iyo laalaabyada periocular.
Habka Waxqabadka:
Muruqa murqaha ayaa dhaca marka neurotransmitter laga sii daayo xuubka synaptik. Isku-dhafka SNARE - shir saddex-geesood ah oo ah VAMP, Syntaxin, iyo borotiinada SNAP-25 - waxay lagama maarmaan u tahay xirashada vesicle iyo exocytosis neurotransmitter (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Kakan waxa uu u shaqeeyaa sidii jillaab gacanta, soo qabata xuubabka iyo isku-dhafka xuubka.
Sida qaab-dhismeedka qaab-dhismeedka SNAP-25 N-terminus, ActiTide™ AH3 waxa ay kula tartameysaa SNAP-25 in lagu daro dhismaha SNARE, iyada oo wax ka beddeleysa kulankeeda. Desbilization of the SNARE complex waxay wax u dhimaysaa xidhidhiyaha xididdada dhiigga iyo sii-deynta neurotransmitter-ka dambe, taasoo keenta hoos u dhaca murqaha iyo ka-hortagga laalaabka iyo samaynta line-ka wanaagsan.
ActiTide™ AH3 waa ka badbaado badan, ka dhaqaale badan, oo ka dabacsan Beddelka Botulinum Toxin Nooca A. Waxa ay si toos ah u bartilmaameedsanaysaa isla dariiqa samaynta laalaabka laakiin waxa ay ku shaqaysaa hab gaar ah.
