| Magaca summada | ActiTide™ AH3 (Liquefied 1000) |
| Lambarka CAS. | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Magaca INCI | Acetyl Hexapeptide-8; Glycerin; Butylene Glycol; Biyo; Hydroxyacetophenone; 1,2-Hexanediol |
| Codsiga | Looshin, Serums, Maaskaro, Nadiifiye Wajiga |
| Xirmo | 1kg/dhalo |
| Muuqaalka | Dareere cad oo hufan oo leh ur astaan u ah |
| Milmida | Biyo milma |
| Shaqada | Taxanaha Peptide |
| Muddada khaanadaha | 2 sano |
| Kaydinta | Weelka ku kaydi si adag oo xiran meel qabow oo qalalan oo ah 2 - 8°C. |
| Qiyaasta | 3.0-10.0% |
Codsiga
Cilmi-baaris lagu sameeyay farsamooyinka aasaasiga ah ee ka hortagga laalaabku waxay horseedday helitaanka ActiTide™ AH3, oo ah hexapeptide cusub oo lagu sameeyay hab cilmiyeed laga bilaabo naqshad macquul ah ilaa wax soo saarka GMP, oo leh natiijooyin wanaagsan.
ActiTide™ AH3 waxay bixisaa waxtar yareeya laalaabyada oo la mid ah nooca sunta Botulinum Toxin A, iyadoo ka fogaanaysa khataraha duritaanka isla markaana bixinaysa kharash-oolnimo badan.
Faa'iidooyinka Qurxinta:
ActiTide™ AH3 waxay yareysaa qoto dheer ee laalaabyada oo ay keento murqaha wejiga oo adkaada, iyadoo saameyn muuqata ku yeelaneysa laalaabyada wejiga iyo qoorta.
Habka Ficilka:
Murqaha oo isku soo urura ayaa dhaca marka neerfaha neerfaha laga sii daayo vesicles-ka synaptic. Isku-dhafka SNARE - oo ah isku-darka unugyada ee borotiinnada VAMP, Syntaxin, iyo SNAP-25 - ayaa lagama maarmaan u ah xidhitaanka vesicle-ka iyo exocytosis-ka neerfaha (A. Ferrer Montiel et al., JBC 1997, 272:2634-2638). Isku-dhafkan wuxuu u shaqeeyaa sidii jillaab unug, isagoo qabanaya vesicles-ka isla markaana kicinaya isku-darka xuubka.
Iyada oo ah qaab-dhismeed qaab-dhismeed oo ka mid ah SNAP-25 N-terminus, ActiTide™ AH3 waxay la tartantaa SNAP-25 si loogu daro dhismaha SNARE, iyadoo wax ka beddeshay isku-xidhkeeda. Kala-goynta isku-dhafka SNARE waxay wiiqaysaa xidhitaanka xididdada dhiigga iyo sii deynta neerfaha ee xigta, taasoo horseedaysa hoos u dhaca murqaha iyo ka hortagga laalaabashada iyo sameynta xariiqda toosan.
ActiTide™ AH3 waa beddel ammaan ah, dhaqaale badan, iyo jilicsan oo ka duwan Botulinum Toxin Type A. Waxay si gaar ah diiradda u saartaa isla marinnada laalaabka laakiin waxay ku shaqeysaa farsamo gaar ah.
