| Magaca astaanta | ActiTide-AH3 |
| CAS Maya. | 616204-22-9 |
| Magaca INCI | Acetyl Hexapeptide-8 |
| Codsiga | Lotion, Serums, Maaskaro, Nadiifiyaha wejiga |
| Xidhmada | 100g/dhalo, 1kg/bac |
| Muuqashada | Caddaan ilaa budo caddaan ah |
| Solubility | Biyo milmaya |
| Shaqada | Taxanaha Peptide |
| Nolosha shelf | 2 sano |
| Kaydinta | Ku kaydi weelka si adag oo xiran meel qabow oo qallalan oo ah 2 - 8 ° C. |
| Qiyaasta | 0.005-0.05% |
Codsiga
Cilmi-baadhis lagu sameeyay hababka aasaasiga ah ee ka-hortagga laalaabku waxay horseedday helitaanka ActiTide-AH3, hexapeptide hal-abuur leh oo lagu sameeyay hab cilmiyeed laga soo bilaabo naqshad caqli-gal ah ilaa wax-soo-saarka GMP, oo leh natiijooyin wanaagsan.
ActiTide-AH3 waxay keentaa waxtarka yaraynta laalaabka oo la barbardhigi karo Botulinum Toxin Nooca A, iyadoo laga fogaanayo khatarta duritaanka iyo bixinta waxtarka-kharashka badan.
Faa'iidooyinka qurxinta:
ActiTide-AH3 waxay yaraynaysaa qoto dheer ee laalaabka oo ay keento foosha muruqa wejiga, oo leh saameyn muuqata oo ku wajahan wejiga iyo laalaabyada periocular.
Habka Waxqabadka:
Muruqa murqaha ayaa dhaca marka neurotransmitter laga sii daayo xuubka synaptik. Isku-dhafka SNARE - shir saddex-geesood ah oo ah VAMP, Syntaxin, iyo borotiinada SNAP-25 - waxay lagama maarmaan u tahay xirashada vesicle iyo exocytosis neurotransmitter (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Kakankan waxa uu u shaqeeyaa sidii jillaab gacanta, oo qabta xuubka xuubka.
Iyada oo ah qaab-dhismeedka qaab-dhismeedka SNAP-25 N-terminus, ActiTide-AH3 waxay la tartameysaa SNAP-25 si loogu daro dhismaha SNARE, iyada oo wax ka beddeleysa kulankeeda. Desbilization of the SNARE complex waxay wax u dhimaysaa xidhidhiyaha xididdada dhiigga iyo sii-deynta neurotransmitter-ka dambe, taasoo keenta hoos u dhaca murqaha iyo ka-hortagga laalaabka iyo samaynta line-ka wanaagsan.
ActiTide-AH3 waa ka badbaado badan, ka dhaqaale badan, oo ka dabacsan Beddelka Botulinum Toxin Nooca A. Waxa ay si toos ah u bartilmaameedsanaysaa isla dariiqa samaynta laalaabka laakiin waxay ku shaqeysaa hab gaar ah.
