| Magaca astaanta | ActiTide-AH3 |
| CAS Maya. | 616204-22-9 |
| Magaca INCI | Acetyl Hexapeptide-3 |
| Qaab-dhismeedka Kiimikada |  |
| Codsiga | Lotion, serums, maaskaro, nadiifiyaha wejiga |
| Xidhmada | 1kg net halkii dhalo /20kgs net per durbaan |
| Muuqashada | Dareeraha/Budada |
| Acetyl hexapeptide-3(8) (Dareere) | 450-550ppm 900-1200ppm |
| daahir (budo) | 95% min |
| Solubility | Biyo milmaya |
| Shaqada | Taxanaha Peptide |
| Nolosha shelf | 2 sano |
| Kaydinta | Ku kaydi meel qabow oo qalalan, oo ka fog iftiinka. 2 ~ 8℃kaydinta. |
| Qiyaasta | 2000-5000ppm |
Codsiga
Hexapeptide ActiTide ee ka hortagga laalaabka-AH3 waxay matalaysaa helitaanka guulo togan oo ku salaysan dariiq cilmiyaysan oo laga soo bilaabo naqshad caqli gal ah ilaa wax soo saarka GMP. Daraasadda hababka biochemical ee aasaasiga ah ee dhaqdhaqaaqa ka hortagga laalaabku waxay keentay hexapeptide-ka kacaanka kaas oo ka qaaday adduunka qurxinta duufaan.
Ugu dambayntii, daawaynta laalaabtay oo la tartami karta waxtarka Botulinum Toxin A laakiin dhinac iska dhaafa khataraha, cirbadaha iyo qiimaha sarreeya: ActiTide-AH3.
Faa'iidooyinka qurxinta:
ActiTide-AH3 waxay yaraynaysaa qoto dheer ee laalaabyada ay keento murqaha murqaha ee muujinta wejiga, gaar ahaan wejiga iyo hareeraha indhaha.
Sidee ayuu ActiTide-AH3 u shaqeeyaa?
Muruqyada waxaa la isku qaadaa marka ay helaan neurotransmitter oo ku socdaalaya xididka xididka. Isku-xidhka SNARE (SNAp RE) wuxuu muhiim u yahay sii-deynta neurotransmitter-ka ee synapsis (A. Ferrer Montiel et al, Joornaalka Kiimikada Bayoloji, 1997, 272, 2634-2638). Waa iskudhaf ternary ah oo ay samaysteen borotiinada VAMP, Syntaxin iyo SNAP-25. Dhismahani waxa uu la mid yahay jillaab gacanta oo soo qabta xuubka xuubka si loo sii daayo neurotransmitter-ka.
ActiTide-AH3 waa shayga N-terminal dhamaadka SNAP-25 kaas oo kula tartamaya SNAP-25 booska dhismaha SNARE, si loo habeeyo samayntiisa. Haddii dhismaha SNARE uu yara xasiloon yahay, vesicle si fiican uma xiri karo oo u sii deyn karo neurotransmitters sidaas darteed murqaha murqaha ayaa la yareeyaa, ka hortagga sameynta xariiqyada iyo laalaabyada.
ActiTide-AH3 waa ka badbaado badan, ka raqiisan, oo ka fudud bedelka Botulinum Toxin, iyada oo si toos ah loo beegsanayo isla habka samaynta laalaabka si ka duwan.
